Shanghai Jinghe Analytical Instrument Co., Ltd
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LC-20 Binary Gradient High Performance Liquid Chromatography
Brief description: LC-20T binary gradient high-performance liquid chromatograph from liquid chromatography manufacturer: The system consists of four p
Product details

LC-20Binary gradient high-performance liquid chromatography

1、 Standard configuration:

High pressure constant flow pump: 2 units

UV detector: 1 unit

System controller: 1 unit

Mixer: 1 unit

8725i manual injection valve: 1 set (optional 7725i manual injection valve)

Chromatography workstation: 1 set

Liquid chromatography column: 1 (C18 4.6 * 250mn, 5um)

Micro injector: 1 unit (50ul/100ul)

Reverse pressure valve: 1 piece

Injection bracket: 1 (for injection valve)

Note: The configuration may vary slightly according to customer needs


Binary gradient high-performance liquid chromatographyIntroduction:

The LC-20 gradient high-performance liquid chromatograph is a new type of liquid chromatograph developed and designed by Shanghai Jinghe Analytical Instrument Co., Ltd. in order to quickly meet diverse customer needs. It is optimized based on the original LC-100 liquid chromatograph and utilizes advanced technology from the United States for domestic processing and production. The application range of gradient system is wider than that of isocratic system. Substances that cannot be separated well by isocratic system can be easily solved by using gradient program. An automatic cleaning program can be set without manually changing the mobile phase, making the cleaning of chromatographic column more convenient. It can be widely applied in various analytical fields such as research and development, pharmaceutical inspection, food testing, chemical analysis, environmental monitoring, etc.

2、 Main features:

Rich features - meeting customers' different analysis needs

The hardware has VP function, which records maintenance information and operation records, in compliance with GLP/GMP requirements; The system controller is equipped with user-friendly design features such as a clock, thermometer, and hygrometer.

Zhuoyue's Performance - Meeting Customers' Strict Requirements for Instruments

The infusion pump adopts a plunger made with consideration of material structure, reinforced PTFE sealing ring, and plunger floating installation method to enhance the stability and durability of instrument performance.

The detector adopts a dual beam monochromator composed of imported deuterium lamps, photovoltaic cells, and 1200/mm concave gratings, a precision machined dual lens flow cell, a high-precision microprocessor for controlling wavelength adjustment, and dual high-speed sampling frequencies to ensure low noise, low drift, and ultra-high sensitivity.

The mixer is mixed evenly, and the baseline collected using gradient program maintains good reproducibility.

Reliable results - meeting customers' accurate requirements for results

Comparative experiments were conducted with imported instruments, and the analysis results showed a high degree of consistency.

Easy operation - convenient for customers to proficiently operate the software

The software adopts a multi window mode, which is easy to operate.

Exquisite appearance - meeting customers' visual requirements for instruments

Exquisite appearance brings visual enjoyment.

3、 Technical indicators:

High pressure constant current infusion pump

Infusion method

Micro volume series double plunger

Maximum infusion pressure

0~6000Psi

Flow setting range

0.001-9.999ml/min (flow rate adjusted in 0.001ml/min steps)

Error in flow setting value

Better than ≤ 0.5%

Flow stability error

Better than ≤ 0.2% RSD

gradient error

± 1% (2 liquid gradient of 0-100% water/acetone solution)

pressure pulsation

Less than 15Psi (flow rate 1mL/min, pressure 600-1600Psi.)

Pump sealing performance

The pressure is 5400Psi, the time is 10 minutes, and the pressure drop is less than 400Psi.

Time program function

have

size

W260×H130×D420mm

weight

11kg

Range of environmental temperature for use

4~40℃

UV Visible Variable Wavelength Detector

wavelength range

190nm~700nm

Wavelength indication error

≤±1nm

Wavelength repeatability error

Better than ≤± 0.1nm

dynamic noise

≤± 0.75 × 10-5AU (methanol, 1ml/min, 254nm, 20 ℃)

Static Noise

≤± 0.5 × 10-5AU (empty pool, response time 1 second, 20 ℃)

Dynamic baseline drift

≤± 1 × 10-4AU/h (methanol, 1ml/min, 254nm, 20 ℃)

Static baseline drift

≤ 0.5 × 10-4 (empty pool, response time 1 second, 20 ℃)

linear range

≥104

minimum detectable concentration

≤ 1 × 10-9 g/mL (naphthalene/methanol solution)

Qualitative repeatability

RSD6≤ 0.1%

Quantitative repeatability

RSD6≤ 0.5%

spectral bandwidth

6nm

Flow pool volume

8μL

optical path

10mm

Time program function

have

size

W260×H130×D420mm

weight

11kg

Range of environmental temperature for use

4~40℃


4、 Software Introduction:

The LC-20 gradient high-performance liquid chromatography dedicated chromatographic data workstation is embedded in the detector, with three sets of VI2010, N2000, and N3000 available for customers to choose from, meeting the needs of different users.

VI2010 L2 is a software with anti control capability used in conjunction with liquid chromatography in the VI2010 chromatography workstation. It has functions such as user account management, password rules, permission settings, electronic signatures, audit tracking, equipment monitoring, system adaptability evaluation, component verification, time program, etc. It meets the requirements of GLP/GMP, FDA, 21CFR Part II, chemical drug CTD format declaration data writing requirements, as well as the basic requirements and management requirements of chromatographic data workstations used in drug registration and declaration research work.


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